Categories
Modern Pharmacology

Diuretics – Mechanism of Action, Types, Classification, Drugs

Introduction A diuretic is any substance that promotes diuresis, the increased production of urine. All diuretics increase the excretion of water from bodies. Such as vasopressin (Antidiuretic Hormone), is an agent or drug which reduces the excretion of water in urine. Mechanism of action First, they effectively reduce blood pressure. Thiazide diuretics are secreted from […]

Categories
Modern Pharmacology

Anti Diarrhoeal – Management, Drug Therapy

Introduction Diarrhoea is too frequent, often too precipitate passage of poorly formed stools. It is defined by WHO as 3 or more loose or watery stools in a 24 hour period. It occurs due to passage of excess water in faeces. This may be due to: Decreased electrolyte and water absorption. Increased secretion by intestinal […]

Categories
Modern Pharmacology

Antiemetic Drugs – Working, Classification

Emesis Vomiting occurs due to stimulation of the emetic (vomiting) centre situated in the medulla oblongata. Antiemetic Antiemetic drugs are types of chemicals that help to cure symptoms of nausea or vomiting. This may also be used to treat nausea and vomiting caused by other medications, frequent motion sickness, infection, or stomach flu. Work These […]

Categories
Modern Pharmacology

Anaesthesia – Work, Classification, Uses

Definition An “Anaesthetic” is a drug used to induce temporary loss of sensation or awareness. They may be divided into two broad classes :- General Anaesthetics= which result in a reversible loss of consciousness. Local Anaesthetics= which cause a reversible loss of sensation for a limited region of the body without necessarily affecting consciousness. Anaesthetics […]

Categories
Modern Pharmacology

General Anaesthesia – Mode of Administration, Classification

Introduction of General Anaesthesia General Anaesthetics (GAs) are drugs which produce reversible loss of all sensation and consciousness. Cardinal Features Loss of all sensation,especially pain Sleep (unconsciousness) Immobility and muscle relaxation Abolition of somatic and autonomic reflexes In the modern practice combination of inhaled and i.v. drugs is used. Mode of Administration Drugs given to […]

Categories
Modern Pharmacology

Sedative and Hypnotic

sedative or transquilliser These are the substance that induces sedation (sleep) by reducing irritability or excitement. They are CNS depressants and interact with brain activity. hypnotic or soporific Hypnotic or soporific drugs, commonly known as sleeping pills. These are a class of psychoactive drugs whose primary function is to induce sleep and to be used […]

Categories
Modern Pharmacology

Anti Malarial Drugs – Objectives and Uses

Defination– Anti malarial medications or simply anti malarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria. Cycle of malaria ANTIMALARIAL DRUGS Chloroquine (CQ) Amodiaquine Piperaquine Mefloquine Quinine Quinidine Proguanil (Chloroguanide) Pyrimethamine Primaquine Tafenoquine Sulfadoxine Sulfamethopyrazine Tetracycline Doxycycline Clindamycin OBJECTIVES AND USE OF ANTIMALARIAL […]

Categories
Modern Pharmacology

Thyroid hormone and Anti Thyroid Drugs

Thyroid hormone Thyroid gland secretes three hormones – T4 (thyroxine), T3 (triiodothyronine) (both produced by thyroid follicle) and calcitonin ( produced by inter follicular “c” cells. Regulation of secretion- Secretion from thyroid is controlled by anterior pituitary, by elaboration of thyrotropin, while TSH ( thyroid stimulating hormone) itself is regulated by TRH ( Thyroid releasing […]

Categories
Modern Pharmacology

Histamine and Anti Histamine – Uses Targets

Histamine definition A chemical found in some of the body cells – causes many of the symptoms of allergies, such as a runny nose or sneezing. When a person is allergic to a particular substance, such as a food or dust, the immune system mistakenly believes that this usually harmless substance is actually harmful to […]

Categories
Modern Pharmacology

Important terms in Pharmacology – Science of Drugs

Pharmacology It is the science of drugs that deals with interaction of exo genously administered chemical molecules with living systems Any single chemical substance which can produce a biological response is a drug. Pharmacodynamics What the drug does to the body. This includes physiological and biochemical effects of drugs and their mechanism of action at […]