SULFONAMIDES Sulfonamides were the first antimicrobial agents (AMAs) effective against pyogenic bacterial infections. Sulfonamido-chrysoidine (Prontosil Red) was one of the dyes used to treat experimental streptococcal infection in mice and found it to be highly effective. Subsequently, an infant was cured of staphylo- coccal septicaemia by protonsil. Short acting (4-8 hr): Sulfadiazine Intermediate acting (8 […]
